OCR GCSE Combined Science Biology, Higher tier sample questions and answers (J250)

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30 sample questions and answers

Taken from every topic of OCR GCSE Combined Science Biology, Higher tier, specification J250. The full guide has 861.

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Paper 7 (Biology)

Cell Level Systems

197 questions in the guide, across 9 subtopics. More from this topic

  1. Microscopy, and sub-cellular structures

    Why does a very active cell such as a muscle cell contain large numbers of mitochondria?

    Show the answer
    Mitochondria contain the enzymes for cellular respiration, so more of them supply more energy for the cell's work.
  2. DNA structure: polymer, double helix and nucleotides

    Give one example of a biological polymer other than DNA.

    Show the answer
    Starch, or a protein.
  3. Enzyme action, and investigating enzymes

    What does the lock and key hypothesis describe?

    Show the answer
    The substrate fits into the active site as a key fits a lock, so only a matching substrate can bind.
  4. Cellular respiration as an exothermic process

    Name three processes in an organism that depend on the ATP supplied by respiration.

    Show the answer
    Muscle contraction, active transport and the building of large molecules such as proteins.
  5. Aerobic and anaerobic respiration compared

    Which substrate is broken down in both aerobic and anaerobic respiration?

    Show the answer
    Glucose.

Paper 8 (Biology)

Community Level Systems

51 questions in the guide, across 4 subtopics. More from this topic

  1. Cycling materials, and the role of microorganisms

    Explain why materials such as carbon and nitrogen must be recycled in an ecosystem.

    Show the answer
    The supply of them is limited, so they have to be returned to the non-living surroundings for other organisms to take up and use again.
  2. Cycling materials, and the role of microorganisms

    How do decomposers return carbon to the air?

    Show the answer
    They respire as they break down dead material, releasing carbon dioxide.
  3. The carbon and water cycles, and decomposition

    Describe how the carbon in a dead animal returns to the air.

    Show the answer
    Decomposers feed on the remains and release carbon dioxide as they respire.
  4. The carbon and water cycles, and decomposition

    Explain why the water cycle provides land organisms with fresh water.

    Show the answer
    Evaporation leaves dissolved salts behind, so the water that condenses and falls as rain is fresh and can be used by organisms on land.
  5. Levels of organisation, and abiotic and biotic factors

    All the oak trees growing in one wood are an example of which level of organisation?

    Show the answer
    A population.

Paper 8 (Biology)

Genes, Inheritance and Selection

118 questions in the guide, across 8 subtopics. More from this topic

  1. Genetic terms, and the genome

    What does homozygous mean?

    Show the answer
    Carrying two identical alleles of a gene.
  2. Genome, environment and mutations

    Explain why height in humans shows continuous variation.

    Show the answer
    It is controlled by several genes acting together, and it is also affected by environmental factors such as diet.
  3. Haploid, diploid and meiosis

    A plant has 14 chromosomes in each of its leaf cells. How many chromosomes are in each of its pollen grain nuclei?

    Show the answer
    Seven, because gametes are haploid and carry half the number found in a body cell.
  4. Single gene inheritance and Punnett squares

    Two black-furred animals produce a brown-furred offspring, where the allele B for black is dominant to the allele b for brown. Explain how this is possible.

    Show the answer
    Both parents are heterozygous Bb, so each can pass on b and produce a bb offspring.
  5. Sex determination and characteristics controlled by many genes

    A Punnett square is drawn for a cross between an XX mother and an XY father. What four combinations fill the four boxes?

    Show the answer
    XX, XX, XY and XY.

Paper 8 (Biology)

Global Challenges

240 questions in the guide, across 13 subtopics. More from this topic

  1. Field investigations, and human impact on ecosystems

    What is a pooter and how does it work?

    Show the answer
    A small jar with two tubes for collecting insects; the user sucks on one tube so the insect is drawn through the other into the jar, and gauze stops it being swallowed.
  2. Maintaining biodiversity, monitoring conservation and ecotourism

    What is ecotourism?

    Show the answer
    Tourism that lets visitors see wildlife in its natural habitat while limiting damage to that habitat and returning money to local people.
  3. Health, disease, and types of disease

    Explain why someone with a poor diet is more likely to catch an infectious disease.

    Show the answer
    A shortage of nutrients weakens the immune system, so fewer white blood cells and antibodies are made to fight the pathogen.
  4. Interactions between diseases, and how they spread

    Explain why a single infected plant can lead to the loss of an entire field of crop.

    Show the answer
    The plants are close together and genetically very similar, so the pathogen spreads rapidly and every plant is equally susceptible.
  5. White blood cells, antibodies and platelets

    What is an antibody, and which cell produces it?

    Show the answer
    A protein that binds to a specific antigen on a pathogen; it is produced by a lymphocyte.

Paper 7 (Biology)

Organism Level Systems

108 questions in the guide, across 8 subtopics. More from this topic

  1. The nervous system and coordinated responses

    What is an effector?

    Show the answer
    A muscle or a gland that carries out the response when an impulse arrives from a motor neurone.
  2. The reflex arc

    Explain why a reflex arc produces a faster response than a voluntary action.

    Show the answer
    The impulse passes through only three neurones and two synapses and does not travel to the conscious part of the brain for a decision to be made.
  3. Hormonal coordination, thyroxine and adrenaline

    Where are the adrenal glands found?

    Show the answer
    One sits just above each kidney.
  4. Hormones in reproduction and the menstrual cycle

    What is the role of progesterone in the menstrual cycle?

    Show the answer
    It maintains the thick lining of the uterus so it is ready for a fertilised egg to implant.
  5. Contraception and treating infertility

    What is sterilisation, and why does it suit only some people?

    Show the answer
    The sperm ducts or the oviducts are cut or tied so gametes can never meet; it is meant to be permanent and is very difficult to reverse.

Paper 7 (Biology)

Scaling Up

147 questions in the guide, across 9 subtopics. More from this topic

  1. Diffusion, osmosis and active transport

    What happens to a plant cell placed in a concentrated salt solution?

    Show the answer
    Water leaves it by osmosis, so the cell loses its turgor and the membrane pulls away from the cell wall.
  2. Mitosis, the cell cycle and cell differentiation

    Why is mitosis important to an organism that reproduces asexually?

    Show the answer
    It produces offspring that are genetically identical to the parent.
  3. Stem cells in animals and meristems in plants

    What are the two things a stem cell can do when it divides?

    Show the answer
    It can make more stem cells, or produce cells that go on to differentiate into specialised types.
  4. Surface area to volume ratio and exchange surfaces

    Why can a single-celled organism rely on diffusion across its surface alone?

    Show the answer
    Its surface area to volume ratio is very large and no part of it is far from the surface, so diffusion supplies its needs fast enough.
  5. The circulatory system, the heart and blood vessels

    Which vessels carry blood away from the heart and which return it?

    Show the answer
    Arteries carry blood away from the heart and veins return blood to it.

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